| 摘要: |
| 六维健康状态分类系统（SF-6D）是常用的健康效用测量方法之一。文章系统介绍SF-6D并概述其在国际上最新的研究及应用进展。相较于欧洲五维健康量表，SF-6D在某些疾病领域测量患者效用值时效度更高、结果更可靠。另一方面，可通过转化文献报导的简明健康状况调查问卷（SF-36）的调查结果来估计SF-6D效用值。用此方法估计患者健康效用值将最大化使用现有的SF-36数据，进而极大节省药物经济学研究成本。但此转化模型是否适合国内研究还有待进一步验证。 |
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| Introduction and research Status of six-dimensional health state classification system |
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| Abstract: |
| Cost-utility analysis (CUA) is widely used for health care decision-maker. However，to ensure the CUA results reliable, an effective measurement of health utility value is needed, even though the measuring process is always complicated and time-consuming. At present, the EuroQol 5 Dimensions Questionnaire (EQ-5D) and the six-dimensional health state classification system (SF-6D) are two of most commonly used utility measures. This research aims to introduce SF-6D systematically and outlines its latest studies and applications. Compared with EQ-5D, SF-6D showed better performance when measuring health state utilities in in various populations and patient groups. Moreover, some scholars estimated the SF-6D utility values indirectly by mapping the SF-36 results reported in the literature. It was proved that the utility value can be used in the study of CUA. Applying this mapping method would sufficiently using existing SF-36 evidence in China for economic evaluation, thus greatly save the cost of CUA research. However, further research needs to verify that this transformation model is suitable for Chinese. |
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