| 引用本文: |
杨燕,何江江,Mark P .Connolly,等.激素补充治疗用于围绝经期综合征的成本分析研究[J].中国卫生经济,2017,(1):44-48.[点击复制] |
.Cost Analysis of Hormone Replacement Therapy for Perimenopause Syndrome[J].CHINESE HEALTH ECONOMICS,2017,(1):44-48.[点击复制] |
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| 摘要: |
| 目的：通过比较激素补充治疗（HRT）和中药治疗围绝经期综合症的成本，评估HRT的经济学效益。方法：本研究基于丹麦骨质疏松预防研究(DOPS)模型，以10万名围绝经期妇女为队列，采用成本效果分析法分析1年期和5年期直接治疗成本和间接治疗成本。结果：在疗效同等的假设下，对比中药治疗组HRT组一年期可减少骨折发生例数60例，减少心血管事件发生数188例，五年期减少骨折发生例数298例，减少心血管事件发生数923例；按65%依从性计算，HRT组相比中药治疗组一年期6631.14万元，可以节约总治疗成本7295.21万元；五年期可以降低药费28541.48万元，可以节约总治疗成本31372.70万元。结论：HRT治疗相比于中药治疗产生的费用更低，且具有良好的远期获益，可以节约卫生资源，减轻患者负担，是治疗围绝经期综合征的较好治疗方案。 |
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| Cost Analysis of Hormone Replacement Therapy for Perimenopause Syndrome |
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| Abstract: |
| Objective: To compare the cost of hormone replacement therapy (HRT) and traditional Chinese medicine (TCM) in the treatment of perimenopause syndrome, and to evaluate the economic benefits of HRT. Methods: Based on the Danish Osteoporosis Prevention Study (DOPS) model, this study enroll in 10, 000 perimenopausal women in the cohort, and analyze direct cost and indirect cost of treatment therapy by cost-effectiveness analysis for a period of 1 year and 5 year. Result: Under the hypothesis of the same treatment effect, compared with the traditional Chinese medicine treatment group and the HRT group, the treatment can reduce fracture in 60 cases and reduce the number of cardiovascular events in 188 cases druing one year; the treatment can reduce fracture in 298 cases and reduce the number of cardiovascular events in 923 cases during five years. Calculated at 65% compliance, HRT group compared with the traditional Chinese medicine treatment group, the HRT group can reduce the cost of 66.3114 million yuan and save the total treatment cost of 72.9521 million yuan during one year.This treatment can reduce the cost of 285.4148 million yuan and save the total treatment cost of 313.727 million yuan during five years. Conclusion: Compared with traditional Chinese medicine treatment, HRT treatment has lower cost and better benefit in the long term. It can save health resources and reduce the burden of patients.It is a good treatment for perimenopausal syndrome. |
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